🤖 GLOBAL HEALTH OPTIMIZATION AGENT v3.0

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🧬 Genetic Analysis

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📊 Resource Allocation by Research Phase:

📚 Data Analysis

🧪 Experimental Design

🔬 Clinical Trials

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Trial Search

Current Search Criteria:

Intervention: Primary Abdominal Closure

Found 60 matching trials

Delayed Primary Versus Late Secondary Wound Closure in Sternum Infections

Sternal osteomyelitis and poststernotomy mediastinitis is a severe and life...

Status

Unknown

Location

Departement of Cardiovascular Surgery, University Hospital Lausanne (CHUV)

Start Date

2012-01

Trial ID

NCT01473979

Treatments Being Tested

Surgical closure of the poststernotomy wound infection

Preoperative BOTOX® Injection for Large Ventral Hernia Repair

PHASE4

This study is for adults who need open surgery to repair a very large abdom...

Status

Recruiting

Location

Cleveland Clinic Main Campus

Start Date

2025-11-03

Trial ID

NCT07220382

Treatments Being Tested

OnabotulinumtoxinA Injection Saline (placebo) Injection OnabotulinumtoxinA 0.9 % Normal Saline Open Ventral Hernia Repair

Using Vaccum Assisted Closure of Wound Instead of Primary Closure as Prophylactic Way Against Burst Abdomen

A vacuum-assisted closure (VAC) device also known as negative pressure woun...

Status

Not Yet Recruiting

Location

Multiple Locations

Start Date

2025-01-01

Trial ID

NCT06732024

Treatments Being Tested

Vaccum assisted closure primary wound closure

Laparoscopic Ventral Hernia Repair with Routine Defect Closure Using Su2ura® Approximation Device

Study includes 5 visits: Screening, Baseline/Surgery, and 14 days, 3 months...

Status

Completed

Location

Hillel Yaffe Medical Center

Start Date

2022-01-19

Trial ID

NCT04986917

Treatments Being Tested

Hernia repair surgery using the Su2ura® approximation device Physical Examination Vital Signs Blood Tests Urine Pregnancy Test Abdominal Ultrasound imaging EuraHS-QoL Visual Analouge Scale (VAS)Clinical evaluation for hernia recurrence and clinical bulging

A Study to Evaluate Adverse Events and Effectiveness of OnabotulinumtoxinA in Participants Undergoing Open Abdominal Ventral Hernia Repair for the Achievement of Primary Fascial Closure Without the Use of Component Separation Technique

PHASE2

Ventral hernias form when there is a loss of integrity of the abdominal wal...

Status

Withdrawn

Location

NYU Langone Hospital - Long Island /ID# 251280

Start Date

2024-05-07

Trial ID

NCT05606757

Treatments Being Tested

BOTOX Dose A Placebo for BOTOX BOTOX Dose B BOTOX Dose C

Outcome of Primary vs Delayed Primary Closure of Laparotomy in Dirty Abdominal Wounds

This randomized controlled trial is designed to evaluate and compare two di...

Status

Completed

Location

Ayub Teaching Hospitql

Start Date

2021-02-17

Trial ID

NCT07531576

Treatments Being Tested

Delayed Primary Laparotomy wound Closure Primary Abdominal Closure

Meta-Analysis on Damage Control Surgery in Patients With Non-Traumatic Abdominal Emergencies

N/A

This systematic review and meta-analysis aims to investigate the effect of ...

Status

Completed

Location

Inselspital, Bern University Hospial

Start Date

2018-04-30

Trial ID

NCT04448912

Treatments Being Tested

Damage control surgery Conventional surgery

A Multicentre, Randomised, Single-blind, Controlled Protocol to Evaluate the Efficacy of Early Administration of Botulinum Toxin for Primary Midline Closure in Patients With Open Abdomen.

PHASE4

A multicentre, randomised, single-blind, controlled protocol to evaluate th...

Status

Not Yet Recruiting

Location

Multiple Locations

Start Date

2025-01

Trial ID

NCT06556030

Treatments Being Tested

Botulinum Toxin A CONTROL

Open Complex Ventral Incisional Hernia Repair Using Biosynthetic Material for Midline Fascial Closure Reinforcement

N/A

Prospective, multicenter, observational study to evaluate performance of GO...

Status

Completed

Location

UCSD Department of Surgery

Start Date

2011-02

Trial ID

NCT01325792

Treatments Being Tested

GORE® BIO-A® Tissue Reinforcement

sIPOM vs pIPOM in Incisional Hernia Patients

N/A

Nowadays, two intraperitoneal mesh approaches are commonly used in Laparosc...

Status

Completed

Location

Multiple Locations

Start Date

2015-01-01

Trial ID

NCT05712213

Treatments Being Tested

Intraperitoneal onlay mesh reinforcement with defect closure before placement of mesh (pIPOM)Standard intraperitoneal onlay mesh repair (sIPOM)

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